Decompensated heart failure in a single center of a Latin American country: findings from the first 1595 cases in the ICARUS registry

Lyda Z. Rojas, Nursing Research and Knowledge Development Group (GIDCEN-FCV), Research Center, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Sergio A. Gómez-Ochoa, Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany; Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Jaime A. Rodríguez, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Karen A. García-Rueda, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Angela M. Torres-Bustamante, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Daniel R. Botero, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
María Cantillo-Reines, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Angie Y. Serrano-García, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Adriana M. Jurado, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Kelly J. Castro, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Katerine Pinilla, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Angie C. Mendoza-Quiñonez, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Nelly J. Vasquez, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Yeinmy Y. Alvarez, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Maribel Rojas, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Diana M. Ortega-Solano, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Yesenia Sanabria, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Angelica Vargas-Sanabria, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Aura M. Cáceres, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Paula S. Bohorquez-Hernández, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Carlos Portillo, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia
Luis E. Echeverria, Heart Failure and Transplant Clinic, Fundación Cardiovascular de Colombia, Floridablanca, Colombia

Objective: Describe the methodological aspects, sociodemographic, and clinical characteristics of patients hospitalized with acute decompensated heart failure (ADHF) and their short-term outcomes. Methods: Prospective cohort of patients with ADHF from the emergency service of the cardiovascular center. Descriptive statistics were used to synthesize sociodemographic characteristics, clinical characteristics during hospitalization, and outcomes. Results: 1595 patients with ADHF. The median age was 68 years (Q1 = 58; Q3 = 76), and 69.28% were men. The median hospital stay was 6 days (Q1 = 4; Q3 = 11), with an cumulative incidence for re-hospitalization at 30 days of 8.70% (95% CI 7.18-10.40%), in-hospital mortality cumulative incidence of 4.33% (95% CI 3.38-5.44%), and a median change in the quality-of-life score Minnesota Living with Heart Failure at 30 days of −20 points (Q1 = −37; Q3 = −5). At discharge, all patients had a percentage > 70% of the use of quadruple neurohormonal blockade therapy. Conclusion: Institutional aCute decompensAted HeaRt FailUre RegiStry (ICARUS) is one of the first studies in Latin America to demonstrate the importance of characterizing the population with ADHF and the adherence to heart failure guidelines may have influenced the favorable clinical outcomes.

Keywords: Heart failure. Heart decompensation. Latin America. Mortality. Hospitalization.